PHAR 562 Lecture Notes - Lecture 9: Arginine, Pyramidal Cell, X-Ray Crystallography
15 Oct 2017
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Document Summary
Voltage-gated ion channels ii: ca & k channels: subtypes, pharmacology and disease. What will we learn: voltage gated ion channel diversity, voltage-gated calcium channels have many diverse family membranes, voltage-gated potassium channels have different membrane topologies, structural basis of ion permeation. It was found that making small changes (switching out amino acids for asparate) to the pore region of prokaryotic. A simplified scheme of t-type ca channel gating. B typical family of whole cell t-type ca currents elicited by stepping from a holding potential of -110mv to a series of incremental depolarisations. Increased firing and upregulation of channels at the gene level in different parts of the reward pathway, which reinforces the desire to get the drug: primary afferent pain sometimes involves upregulation of ca channels. Ca channels and drug addiction: da neurons in the vta project to nacc and.
