PHAR 505 Lecture Notes - Lecture 1: Drug Design, Protein Purification, Drug Discovery

• School: McGill University
• Department: Pharmacology and Therapeutics
• Course: PHAR 505
• Professor: Jean Francois Trempe

Document Summary

Weeks 1-3 section 1, principles of structure-based drug development: core principles of biomolecular structures. Interactive session with molecular graphics: protein purification, quantification of drug target interactions (2, first assignment covers material from weeks 1-3, due october 3, 2017. Weeks 6-9 section 1, principles of structure-based drug development: structural methods (3, drug design principles (2, writing clinic. Interactive session with molecular graphics: computational approaches, third assignment covers material from weeks 6-9, due november 7, 2017. **written report to be submitted on nov 30th at the beginning of class. Consider the assignments as practice for the final exam. Consist of problem solving and short answers on the principles of structure-based drug design taught in class. Write a short abstract (1500 characters) of a research article chosen from a list of articles provided at the beginning of the term: same article will be used for the written report (20%)