PHAR 303 Lecture Notes - Lecture 22: Phthalate, Canadian Environmental Protection Act, 1999, Precautionary Principle
8 Apr 2016
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Document Summary
The systematic scientific characterization of potential adverse health effects from human exposures. Risk is the probability of an adverse outcome under specified conditions. Risk management is the process by which policy actions are chosen to control hazards. Objective of risk assessment: protect human and ecological health, toxic substances, balance risks and benefits, drugs, pesticides, set target levels of risk. Food contaminants: water pollutants, set priorities for program activities, regulatory agencies, manufacturers, environmental/consumer organizations, estimate residual risks and extent of risk reduction after steps are taken to reduce risks. Characterization of the innate adverse toxic effects of agents: weight-of-evidence approach. If you have one good animal study and no human studies for a particular chemical, you would say that it possibly causes cancer. If you have some evidence in human studies or two or more good animal studies, you would say it probably causes cancer: good evidence in human studies would cause the chemical to be known to cause cancer.
