PHAR 303 Lecture Notes - Lecture 19: Hyperthyroidism, Gonocyte, Thyroid

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Can find receptors for steroid hormones in many parts of the brain. The hypothalamus will talk to the pituitary which will put out a bunch of hormones which will affect endocrine tissues (e. g. thyroid, pancreas, adrenal, testes, ovaries) Bone, heart, liver, and fat are all also part of the endocrine system; they put out signals to the rest of the body as well. A hormone is put out, it stimulates a cell (e. g. leydig cell) to secrete steroids, the steroids feeds back to turn off the secretion of the hormone. In the absence of the steroid, the pituitary or hypothalamus will induce the production of the hormone to stimulate the cell. The who acknowledges the effects of endocrine disruptors on health. Endocrine disrupting chemicals (edc) in the everyday environment: pahs, plasticizers, cleaning products, bisphenol a, air particulates, ozone, flame retardants, pharmaceuticals, pesticides, herbicides, fungicides. The effects of early exposures to edcs may be manifested any time in life.

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