PHAR 301 Lecture Notes - Lecture 9: Myosin Light Chain, Calcium Channel Blocker, Bronchial Hyperresponsiveness
Document Summary
It"s an acute problem that needs an acute solution. You can open up the pipes (broncho-dilation therapy) Opening up the airways doesn"t solve the disease - it deals with the symptoms of the. The second component is the inflammation situation which is the underlying cause of the disease disease. 1 out of 4 children have asthma o. It usually happens to poor people in rich countries. This has been an area of very intense research which is still unresolved. Ige then interacts with mast cells that have a receptor for it o. When there is an interaction between an allergen, an ige receptor, and a mast cell, the mast cell will degranulate (this is a regular allergic response) This is the response to allergies - asthma is not quite the same but the same cellular o. This triggers the release of many inflammatory mediators which will cause bronchoconstriction and components are used inability to breathe know what the allergen is.