PATH 300 Lecture Notes - Lecture 4: Vasoactivity, Leukotriene, Chemokine Receptor

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Reading: chapter 3 (all of this is extremely well covered in the textbook) [aka: granulocyte) become apoptotic, they are followed by monocytes and macrophages, followed by repair: not much repair needed after the bite since it is minor inflammation. These mediators need to be coordinated they have to signal each other all the time to coordinate this response. We are going to look at the major classes of compounds, and some of the most significant representatives of these classes of compounds. Lysis of bacteria (cause their destruction), chemotaxis (pulling in other cells like neutrophils and macrophages), opsonization (make microbes recognizable by phagocytic cells for destruction) Complement is activated at the site of inflammation. It can be activated with the classical pathway, which we"ve looked at. It can also be activated by the alternative pathway, which functions at the level of.

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