PARA 438 Lecture Notes - Lecture 23: Giardia Lamblia, Antimicrobial Peptides, Transporter Classification Database

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Parasite: an organism that lives on or in a host and gets its food from or at the expense of its host. Malaria [plasmodium spp. ] is infecting 10% world population; have acute clinical signs. They live in the host, not kill it. If they are not in the host may induce more severe immune reaction. Immunosuppression - state of tolerance (mainly chronic disease, not acute) Athymic mice: have very low tc number --chronic infection --->tc is essential to clear infection. Have low account of cd4tc ---late-stage hiv infection -->cd4 is essential to clear infection. Ifn gama--->absence cause susceptible to infection; essential to protect against disease. Cryptosporidiosis: have high igm, igg, iga during infection (not ige); igg high for several months. Anti-c. parvum: protect calves from cryptosporidiosis; but not essential for resistance against infection; help immunocompromised individual to recover. Hiv patient: if treated with colostrum, but will continue to have chronic disease, can"t clear the immune response.

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