PARA 410 Lecture Notes - Lecture 4: Apicomplexan Life Cycle, Macroparasite, Ascaris
10 Feb 2020
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Document Summary
Single celled eukaryotes (have a nucleus: have a nucleus = fundamental difference between them and bacteria. Fit in with viruses and bacteria as typical mico-pathogens. They are free living some are parasitic or symbiotes (presence benefits the host) Transmission by ingestion- live in intestine: could also be in blood like malaria, fecal-oral transmission. Gastrointestinal protozoa [cyst ingested trophozoite cyst and release in feces] Ingest of free-living cyst that lives in water/ soil etc. that has some protective features allowing it to survive for months. Once ingested the cyst transitions into a trophozoite that replicates in the intestine: they divide over and over again even if you only ingest one cyst. Cysts are highly infectious only a few lead to infection. Daly: disability adjusted life years, morbidity disease, mortality death, used to compare burden of disease with different infections. Takes a few weeks for it to travel to gut.
