MIMM 214 Lecture Notes - Lecture 37: Mast Cell, House Dust Mite, Adaptive Immune System
8 Apr 2017
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Document Summary
Allergies: th2 responses (seen in lecture 22) tend to be involved in allergic responses, recall the hygiene hypothesis and use of helminths in treatment of allergy, functions of th2 cells: Induction of epithelial cell repair and mucous secretion (il-13) Ige abs are secreted by the plasma cells. If there are fcrs on the surface of mast cells, there must have been an adaptive immune response earlier on. Mast cells release their granule contents and depending on the nature of the allergen, route of exposure and location of the mast cell, there can be different effects. Git increased fluid secretion and muscle contraction in the gut. Airways congestion, blockage, swelling, mucous secretion, sneezing. Blood increased blood flow and permeability anaphylactic shock most severe case. Route of entry of allergen will determine the sxs of an allergic response. Inhalation bronchial smooth muscle contraction, increased mucous production asthma or allergic rhinitis.
