MIMM 214 Lecture Notes - Lecture 17: Endothelium, Regulatory T Cell, Signal 1
17 Feb 2017
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Mt = 50 minutes, 30 mcqs, anything covered in class and the assigned readings = fair game. Many questions will resemble the qs we do in class. Review your formative assessments and the practice qs created by the team members (have not seen the exam) Some rote knowledge qs and some where you need to look at data and analyse it. We"ve spent a lot of time talking about activation and now we will start talking about differentiation and the formation of effector cells and their activity activating macros and. Different effector fxns of different t cells: activation of. B cells, activation of macros, kill infected cells directly. Egress to site of infection (leaving the ln) Cell-mediated immunity: th2 cytokines promote tc killing & macro ros killing (intracell pathogens) Humoral immunity (hmi): abs promote pathogen neutralisation, opsonisation and complement activation. Downregulation of t cell activity and immunological memory. All three signals result in intracellular signaling leading to a change.
