MIMM 211 Lecture Notes - Lecture 30: Streptococcal Pharyngitis, Aureus, Chemotherapy
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Mimm 211 antimicrobial chemotherapy: compounds & resistance (11/19/18) If we are not careful, we will soon be in a post-abx era and for some patients and for some microbes, we are already there cdc. A post-abx era means an end to modern medicine as we know it. Things as common as strep throat or a child"s scratched knee could once kill. Replacement therapy are more costly, more toxic and need much longer duration of tx. Over a century later, resp infection and diarrhoeal diseases are still among the top killers even in the developed world! Sir howard florey and ernst chain, 1939-1940 isolation of penicillin: wwii 1942-1945, many soldiers would die from wound infections. Coconut grove fire in boston, 1942: 492 people died, many of these people died due to burn wound infection, first real use of penicillin in the medical community outside of battlefield hospitals.