INDS 212 Lecture Notes - Lecture 50: Fetal Alcohol Spectrum Disorder, Substance Abuse, Delirium Tremens

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Alcohol alcohol use disorder, intoxication, withdrawal, delirium, alcohol induced persisting amnestic disorder. Introduction: problematic alcohol use in students (see table, canadian epidemiology (2012): alcohol use. Aud: 2. 6% (3. 8% for men, 1. 3% for women: us data from 2006: 1 year prevalence of aud: Effects of alcohol use: short term: intoxication, injury, violence, accidents, spousal abuse, suicide, alcohol toxicity (overdose), death. Intoxication: problematic behaviour and psychological changes, slurred speech, incoordination, Alcohol withdrawal: symptoms: sweating and increased pulse, increased tremor, insomnia, nausea and vomiting, hallucinations, Alcohol induced persisting amnestic disorder: wernicke encephalopathy, acute and reversible, due to lack of thiamine, confusion, ophthalmoplegia and ataxia, korsakoff"s syndrome, chronic (10% recover completely, amnesia, confabulation, apathy, and anosognosia. Treatment of alcohol use disorder: first-line treatments, naltrexone: blockage of mu opioid receptor, blocks the reinforcing effect of alcohol, acomprosate: gaba agonist and glutamate antagonist, second-line treatments: disulfuram, topiramate, gabapentin, baclofen.

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