INDS 212 Lecture Notes - Lecture 44: Tardive Dyskinesia, Quetiapine, Antipsychotic

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Indications for antipsychotics (fga: first generation antipsychotic; sga: second generation: psychotic illnesses: schizophrenia; bipolar disorder; psychotic major depressions; delusional disorder. There are indications but : risk of drug-induced parkinsonism 25-30% (fga) vs 5-10% (sga), except for clozapine and quetiapine (no, major depression, non-psychotic: especially if non-responsive. ): particularly the more sedative ones, in small doses (eg. quetiapine) risk) bilateral: symptoms of drug-induced pd vs pd: less on and off, not progressive, less gait instability, often. This happened more when we overmedicated patients, especially in women and the elderly: there are also psychosocial interventions with evidence base. During the first episode, almost any constipation, which may even happen at low doses) medicine works well (fga, sga). The more relapses you may have, the more resistant the illness is. 1 number of antipsychotic trials) normodopaminergia non responsive or very partially responsive to clozapine.

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