EDKP 449 Lecture 18: 1) EXERCISE PATHO 2

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Mi3 laboratory - mitochondria for oxidative phospho - aerobic respiration. *no mitochondria = only rely on anaerobic glycolysis & impacts ability to produce energy. Fact: ~630 muscles 30-40% body weight - used for support/organs not only for movement. O2 lung for ventilation cardiac distribution & circulation of blood feed mitochondria. *all cells = have mitochondria except for rbc - red blood cells *use hemoglobin. Cross section of skeletal muscle - tendon attached to bone. Only 1 nuclei - line organs & blood vessels to coordinate functions throughout cell. *sarcomeres only in striated & cardiac muscle fibers. Neuromuscular junction - motor neuron to skeletal muscle. 3- na+ influx through activated nicotinic acetylcholine receptors (nach) Calcium regulated at troponin located on actin-containing w/ striations. Voluntary contraction via axons terminals of somatic nervous system. Slow to fast contraction no rhythmic contraction/ pacemaker. Openings- connect inside & outside to enter cell. Releasing ach & binding of ach to post-synaptic.

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