BIOC 311 Lecture 36: Glucose

• School: McGill University
• Department: Biochemistry
• Course: BIOC 311
• Professor: Julie St- Pierre

Document Summary

Glut2 is in the pancreas and it senses the amount of glucose in the blood so the pancreas will know when to release insulin. The increase of glucose levels in the bloodstream after a meal stimulates the glucose transporter. Glut2 of the beta-islets of langerhans cells in the pancreas. Glut2 will bind glucose and bring it to insulin-responsive tissues. Regulation by insulin of glucose transport by glut4 into adipocytes and muscle cells. Insulin stimulation of adipocytes results in the translocation of the glucose transporter glut4 from the intracellular storage sites to the plasma membrane. The islets of langerhans of the pancreas contain endocrine tissues: alpha, beta and gamma cells. When the glucose level in the blood drops below a certain level, the pancreas secretes glucagon. Glucagon is released from alpha-cells of the pancreatic islets of langerhans in response to reduced levels of blood glucose, and it stimulates glucose production and glycogen breakdown in the liver.