ANAT 381 Lecture 2: 2- Lecture 2

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In the early stages of development, next to the gonad is the mesonephros. In females, ultimately, each oocyte is enclosed in a small number granulosa cells . Female germ cells are not totally individualised: when they undergo mitosis, they don"t completely separate form germ cell nests (due to incomplete cytokinesis). The cells become attached, with some sort of communication between each other. Around that stage of individualisation is when the oocytes enter meiosis (before. The male germ cells stop proliferating mitotically before birth, but don"t enter meiosis. later, the male germ cells resume proliferating mitotically. In females , the eggs are out of mitotic cycle before birth. When a female is born, she"s born with the total number of oocytes she"ll ever have (entered meiosis before birth). no new oocytes are made after birth. Embryonic oocytes become arrested part-way through meiosis. Timeline of the development of primordial germ cells into female and male germ cells.

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