ANAT 321 Lecture Notes - Lecture 12: Opsin, Lisa Lopes, Anatomical Terms Of Location

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= perfect example of lateral inhibition by increasing difference b/w. Activation of center & surround region amplify signal-noise ratio. *different bipolar cells = either (+) or (-) synapse so determine if on/off-center & polarity. So main difference for on-& off-centered = type of bipolar cells (+) or (-) Each 1 cone forms center of 2 rgc = a) on-centered & b) off-centered pathway: on-centered = (-) glutamate synapse, off-centered = (+) glutamate synapse. Center & surround of receptive field of 1 rgc from 1 photoreceptor. Result = each cone very sensitive to change & edges of light from dim bright & bright dim. *cones can detect light going in both directions [increase/decrease] because of 2 connections. *same basic connectivity as inside fovea but larger range to detect & in illumination. Many rods forms center of a) on-centered & b) off-centered pathway. Center & surround of receptive field of 1 rgc from many photoreceptors.

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