CHEM 212 Lecture Notes - Lecture 19: Primary Alcohol, Hyperconjugation, Geminal

• School: McGill University
• Department: Chemistry
• Course: CHEM 212
• Professor: Jean- Philip Lumb

Document Summary

If the 2 subsituents with highest priority are located on: Tetrasubsituted > trisubsituted > disubsituted ( geminal > trans > cis. H has no chance for hyperconjugaion; subsituents do. Zaitsev"s rule e2 w/ unhindered base most stable alkene. Hofmann"s rule e2 w/ hindered base least stable alkene. Zaitsev"s case kineic product = thermodynamic product. Hofmann"s case kineic product thermodynamic product. E1 coplanar; bond forms from 2 p-orbitals; e/z mixtures. Primary alcohol: dehydraion: no strong base -> slow-paced. + + bonds / linear / sp hybridizaion. Hybridizaion sp > sp2 > sp3 in s characterisics / acidity / low pka. Because of the short bond length, alkynes with its h+ detached store its negaive charge closer to the posiive nucleus. Sp c-h acidity synthesis / reacivity. Best way to obtain from alkyl halides. Geminal dihalides e2 of h-c-x (anicoplanar) *2 |ani-eliminaion. Vicinal dihalides e of h-c-x(coplanar)*2 | syn-eliminaion.