CHEM 181 Lecture Notes - Lecture 2: Chlorpromazine, Clomipramine, Maurice Wilkins

• School: McGill University
• Department: Chemistry
• Course: CHEM 181
• Professor: David Harpp

Document Summary

William harvey: first to ling heart and circulatory system. Diabetes: treatments: insulin for type 1 diabetes. Hypercholesterolemia: statin drugs (lipitor): reduce blood cholesterol, reduce risk of strokes. Nnt: should be one but is 150. Homocysteine: naturally occurring compound in our body. Increases in absence of vitamin b, taking vitamin b doesn"t effect heart disease. In ammation: measured by c-reactive protein, >100mg/l is linked to heart diseases. Hypertension: sbp-dbp: 120/80 mm hg, in hypertension >140/90 mm hg: exercise, diet, salt intake, medications: Diuretics: inhibit kidney retention of salts, pee, less uid in body, lower bp. Ace inhibitors: inhibit angiotensin 2, chemical that increases bp, lower bp. Calcium channel blockers: block cal entry, dilates vessels, lower bp. Beta blockers: blocks action of adrenalin, lower bp. Angiotensin receptor antagonists: blocks angiotensin 2, binds to receptor sites, Angina: characterized by chest pain, not enough oxygen in blood: coronary artery occlusion: atherosclerosis: normal - fatty streak - atheroma -