BIOL 306 Lecture 33: Lecture 33
10 Jan 2019
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Document Summary
It is how organisms tell the time, an internal clock. Locomotion and metabolism of organisms reflect circadian rhythm: ex: locomotor activity in drosophila active in 24 hours cycles, rodents are active at night, more running on the wheel at the night. Do experiment: molluscs active at night, try: Circadian cycle is retained for many days, so it"s not the slave model, and it"s not 100% autonomous. The basal retinal neurons (which have 24-hour cycles even in darkness. Membrane potential changes during the day: before dawn, there is a very low resistance of the membrane. Add potassium blocker you convert to the membrane (channels open, high conductance) resistance of after dawn: after dawn, there is a high resistance of the membrane. Alanna watt, joe dent, tomoko ohyama: 4 phenotypes: Per acts in a brain through a diffusible substance. If you transplant a wild-type brain and transplant it into the abdomen of a null mutant, you can recover the 24-hour cycle.
