BIOL 202 Lecture Notes - Lecture 18: Meiosis, Zygosity, Phenotype
Document Summary
Chromosome have trouble pairing up, but when they try to line up the sequences, they form inversion loops: paracentric. Genes are not in the same sequence problems in crossing over. One of the crossing over product have two centromeres. Acentric fragment doesn"t have centromere, and is lost: pericentric. Inversion can suppress recombination in heterozygous no viable crossover products; can be used as a balancer in test cross. Translocation: breakage on two different chromosomes pericentric (non-homologous) In meiosis, the equivalent parts try to pair up two different chromosomes line up together: decreased fertility. If segregation results in duplication and deletion, the product is often inviable. A normal gamete and a translocation gamete can be viable but a translocation carrier (e. g. in down syndrome: decreased recombination. Where do mutations come from: fluctuation experiment. Grow e coli culture with the presence of bacteriophages.
