BIOL 201 Lecture Notes - Lecture 28: Axoneme, Aeronautical Accidents Investigation And Prevention Center, Cell Cortex
Document Summary
Ends at centrosomes fourth generation interaction between microtubules and plasma membrane. Mitosis: interphase long stable, non polarized microtubule network emanating from a single centrosome. Begin by duplicating the centrosomes at same time you replicate dna, they are side by side though so they need to push off and walk across the nucleus: prophase. Push off from one another and walk to the ends. Microtubules overlap and motors push them away. Now centrosomes at opposing poles chromosomes condense: prometaphase. Spindle would be longer because you are pushing on the centrosomes outwards and elongates: if removed it will collapse, pulling by dynein. Kin-5 will bind to axoneme and free microtubules put on the slide that are themselves bound to antibody b that recognizes microtubule. Over time see microtubule marching along axoneme. Kin-5 can bind 2 things and move them along. Major role for dynein: in placing spindle at right place and cell type: e. g.