BIOL 201 Lecture Notes - Lecture 13: Leading Edge, Model Organism, Cell Migration
19 Apr 2018
School
Department
Course
Professor
Document Summary
Chemotaxis: process by which a cell moves to a chemical signal to which they like. Actin filaments extend the lamellipodium and pull the cell forward. The cell contracts to pick up its back foot and move its cell body forward. Stress fibers are actin bundles that contract and produce force. Contractile bundles have the actin filaments in red and the myosins in blue. These are connected to protein complexes called integrins that act as the cell"s foo are part of the focal adhesions; they extend across the plasma membrane & bind directly to the extracellular matrix. To understand how these work we need to know: How they make long bundles of actin filaments & how the parallel arrays are formed. s foot & ind s are formed. The fh2 purple formin dimer pops up & down to control the rate at which actin monom bind.
