BIOL 201 Lecture Notes - Lecture 12: Chemiosmosis, Porphyrin, Mitochondrion

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Redox coupling: the energy released by the oxidation of nadh to nad, allows for the proton pump to pump into the intermembrane space. Proton conc. is higher in the intermembrane space, and has a lower ph. 1,3,4 are the 3 complexes that pump protons. The free energy from succinate to fum arate is not enough to pump a proton, this happens at 2. Catalyzes transfer of electron from nadh to coq. Nadh + coq + 2h - > nad + h + coqh2. The 2 electrons and one proton is first transferred to flavin, a triple ring compound. 9 iron-sulfur centres are part of complex 1. 7 of which are involved in the electron transfer. Ferric to the ferrous state and then passed on. Cytochromes have 2 other forms, which are embedded in the membrane. C-type has covalently bound cytochromes, while b-types have non-covalently bound heme.

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