BIOL 112 Lecture Notes - Lecture 2: Van Der Waals Force, Carboxylic Acid, Protein Folding

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BIOL 112: LECTURE 2
Ionic Bond: creates an electrostatic attraction between the +/- ions (e.g. NaCl)
- Group 2 makes salts (MgCl2 stronger bond than NaCl)
- Very strong, attraction to opposite charges HOWEVER amino to carboxyl group is WEAK
Hydrophili ater-loig: POLAR COVALENT
- partial negative and partial positive charges; polar molecules and ions dissolve readily in
water (e.g. salt is dissolved in water)
- water is a great solvent
Hydrophoi ater-hatig: NON-POLAR COVALENT
- do not dissolve in water
- tend to cluster together to avoid the water (e.g. oil stays in bubbles on the top)
Hydrophobic Interaction:
- all the non-polar oalet ods are oig together, lusterig, to aoid ater,
minimizing the disruption of the surrounding network of hydrogen bonds
- important for protein folding & membranes
Van der Waals Interaction:
- non-polar molecules attracted to each other weakly (transient dipoles)
- attraction due to fluctuating electrical charges
In Bio: Covalent Bonding > Hydrogen Bonding > Ionic Bonding > Van der Waals
Chemical Reactions:
- an equation that balances (conservation of chemical energy)
Molarity:
- one mole of one substance in one litre of water = 1 M
- mole = atomic/molecular weight in grams (g)
Acids:
- Acids release/donate H+ ions in solution
o Complete dissociation = strong acid (e.g. HCl)
o Partial/Reversible dissociation = weak acid (e.g. ---COOH)
Can reform & go in both directions (e.g. COO- + H+)
Bases:
- Bases accept H+ in solution (release OH-)
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BIOL 112 Full Course Notes
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Document Summary

Ionic bond: creates an electrostatic attraction between the +/- ions (e. g. nacl) Group 2 makes salts (mgcl2 stronger bond than nacl) Very strong, attraction to opposite charges however amino to carboxyl group is weak. Partial negative and partial positive charges; polar molecules and ions dissolve readily in water (e. g. salt is dissolved in water) Do not dissolve in water tend to cluster together to avoid the water (e. g. oil stays in bubbles on the top) All the non-polar (cid:272)o(cid:448)ale(cid:374)t (cid:271)o(cid:374)ds are (cid:272)o(cid:373)i(cid:374)g together, (cid:862)(cid:272)lusteri(cid:374)g(cid:863), to a(cid:448)oid (cid:449)ater, minimizing the disruption of the surrounding network of hydrogen bonds important for protein folding & membranes. Non-polar molecules attracted to each other weakly (transient dipoles) In bio: covalent bonding > hydrogen bonding > ionic bonding > van der waals. An equation that balances (conservation of chemical energy) One mole of one substance in one litre of water = 1 m. Mole = atomic/molecular weight in grams (g)

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