PSYC-307 Lecture Notes - Lecture 10: Prediabetes, Fibrinogen, Prodrome

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Thus the rise of psychoneuroimmunology: mind body and health are bidirectional and influential on each other. Chronic stress impacts immunity: common neural subsrate between stress and immunity. Cognitions, appraisal, perceived threat, and negative emotions such as hostility, anhedonia these intensify stress reactions. T cells and b cell counts will be low and the person is unequipped to deal with illness. Overtime impairs cortisol and anti-inflammatory response (ex cortisol resistance like drug tolerance, reduces anti-inflammatory response) Chronic stress causes illness: allostasis: internal reactions needed to maintain physiological stability (homeostasis the oldconcept ex it is natural for body temp to range throughout the day). With high stress, more effort is used by the body to try and maintain allostasis. How much is the body wearing out by trying to reach allostasis more processed food during exam times, sleep deprivation) How do we measure allostatic load: early signs, prior to diagnosis. The sum of the whole far higher than the parts.

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