PHED-4547EL Lecture Notes - Lecture 6: Innate Immune System, Autoimmunity, Body Fluid
27 Apr 2020
School
Department
Course
Professor
Document Summary
Chapter 6 immunity, hypersensitivity, allergy and autoimmune diseases. Two separate mechanisms function together to protect us from disease. Immune system cannot distinguish the self from foreign material. Hypersensitivity: abnormal reaction to a foreign material (which is not necessarily harmful, excessive immunity , allergic responses such as hay fever. Antigen must first be processed and displayed on the cell membrane of the antigen processing cell before the immune response can be set in motion: toxic or foreign substance. Lymphocytes interact with the antigen they are programmed to recognize. When appropriately stimulated: b lymphocytes proliferate and mature into antibody-forming plasma cells, t lymphocytes proliferate to form a diverse population of cells that regulate the immune response and generate a cell-mediated immune reaction to eliminate antigen. Initial contact with a foreign antigen is followed by a lag phase of a week or more before an immune response is demonstrated: two-step tb test.
