PHYL 2041 Lecture Notes - Lecture 5: G Protein–Coupled Receptor, Myasthenia Gravis, Neuromuscular Junction

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24 Sep 2018
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4phyl 2041 lecture 5 neurotransmitters and their receptors. The textbook states that potential at which each ion has no net flow through the membrane, the equilibrium potential. If the channel only conducts one ion, like potassium channel, then the reversal potential of the channel would be the equilibrium potential of potassium. If the channel conducts more than one ion, sodium and potassium, for instance, then the reversal potential would the weighted mean of the equilibrium potentials of the ions and could be calculated by the chord conductance equation. A combination of temporal and spatial summation can lead to an action potential. Cholinergic neurons in the vertebrate nervous system: motor neurons, autonomic nervous system. Postganglionic parasympathetic neurons: neurons regulating arousal and sleep in brainstem and basal forebrain. Local interneurons in other brain regions (ex. striatum) Neurons that employ acetylcholine, so called cholinergic neurons are distributed widely within the nervous system. For one, motor neuron use acetylcholine as nt.

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