PHAC 4001 Lecture Notes - Lecture 25: Natural Killer Cell, Calcineurin, Calcitriol Receptor
12 May 2021
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Phac 4001 lecture 25 march 19, 2021 immunopharmacology and anti-viral drugs i. Overview: general overview of the immune response, categories of drugs, drugs used in treatments of hiv, autoimmune diseases, transplantation, asthma, other viral infections. Louis pasteur later exploited these observations in developing vaccination and germ theory of diseases: 1891: robert koch published proof that microorganisms caused infectious diseases. Paul erlich: noted for curing syphilis and research into autoimmunity (called "horror autotoxicus , side-chain theory: living cells have side-chains in the same way dyes have side-chains which are related to their coloring properties. These side chains can link with a particular toxin. Deficient immunity results in increased susceptibility to infections; exemplified by aids. Vaccination boosts immune defenses and protects against infections. Clearance of dead cells and tissue repair deficient immunity can lead to secondary infections after injury, and. The immune system can injure cells and induce pathologic inflammation.
