PATH 3000 Lecture Notes - Lecture 21: Bone Marrow, Rheumatoid Arthritis, Periosteum
Document Summary
Path 3000 lecture 21 march 6, 2020 bones and joints pathology. Bones: adult humans have 206 bones, 12% of body weight, bones can be divided into, 10% replaced annually, long bones (predominantly appendicular, ex. femur, radius, flat bones (predominantly axial, ex. skull, pelvis) Bones are also constantly changing - there are 10% of bones replacement and turnover each year. Structure of bones: outer layer of periosteum, cortical bone layer, medullary layer, bone marrow. There is an outer layer of periosteum, which is a fibrous tissue. There is a cortical bone layer and is strong, thick to provide support. The medullary bone layer is thinner and supports the bone marrow, which is involved in producing blood cells. The periosteum, which is the dense fibrous tissue, will connect with to the tendons (connecting bones to muscles) for stability and movement. The cortical bone layer is the outer layer of bones that provide most structural support and strength.