PATH 3000 Lecture Notes - Lecture 1: Necrosis, Rudolf Virchow, Cytopathology

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Path 3000 lecture 1 january 10, 2020 cell, pathology, part 1. Pathologists experts in tissues (diagnosing cancer comprises ~50% of the job) Outline: structure and function of normal cell, organelles. Integration and coordination of cell function; response to injury: reversible. Rudolf virchow (1821 1902: physician and biologist (and anthropologist , considered father of modern cellular pathology. What is a cell: basic functional unit of the body, consists of smaller functional units called organelles, some can be seen with light microscope, require electron microscope for most. The left shows a normal section of the small bowel. The nutrients go through from the microvilli and enter into the wall of the small bowel. Advanced form of celiac disease would have no to little microvilli. In the small bowel, the microvilli are called enterocytes. Structure and function of a cell: endoplasmic reticulum, golgi apparatus, lysosome, cytoskeleton, nucleus, cytoplasm, mitochondria, ribosome, plasma membrane.

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