CH&E 4010 Lecture Notes - Lecture 9: Randomized Controlled Trial, Amenable Group, Recall Bias
Document Summary
Ch&e 4010 lecture 9 february 8, 2021 developing a research question: finer. Learning objectives: review the motivation of epidemiological research, describe the design of cohort studies, discuss potential biases in cohort studies. Illustrate the cohort study design using important historical examples. Randomized controlled trial controls for main forms of bias. Quasi-experimental studies can use natural experiments selection bias - experimental and. Can establish temporal sequence (exposure precedes the outcome) can estimate incidence. Representative - can cover whole population (or sample) control groups different. Time consuming, expensive selection bias - loss to follow-up. In addition to the fundamental pico (population, intervention (exposure), comparator, outcome: additional considerations for developing a good study question, tip: consider these elements in your research design challenge proposal. Developing a research question: finer: f -feasible, adequate number of subjects, adequate technical expertise (ex. Methodological skills, clinical skills, etc: affordable in time and money, manageable in scope. In reality, we are restricted by budget (k, k, m?)