BIOL 2030 Lecture Notes - Lecture 9: Mendelian Inheritance, Contingency Table, Pupa
4 Feb 2016
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When there is linkage, more gametes will be parental than recombinant o. Sometimes, linkage configuration can be deduced from the parental cross that created the double heterozygotes: tomato plants with2 genes. Testcross: md/md x md/md: other times, the linkage configuration has to be deduced from results. Non-recombinant (parental) progenies should be more numerous. Testing for linkage or independent assortment between 2 genes with chi-squared. If in a testcross we see too many parental and too few recombinant types linkage: chance could also lead to deviations from results expected with independent assortment. A 2 test of independence can be used to evaluate whether the segregation of alleles at one locus is independent of the segregation of alleles at the other locus. Over small distances, r increases as the distance between loci. R can be used as a measure of genetic distances between.
