BIOL 2030 Lecture Notes - Lecture 18: Philip Leder, Stop Codon, Start Codon
6 Mar 2017
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Lecture questions: d, alternative splicing increases number of proteins that could be produced from the same mrna, transcription initiation, mrna capping on 5" end, mrna splicing, mrna polyadenylation, then nuclear export, and translation initiation, b, c. Triplet code: three consecutive ribonucleotides (codon) specifies one amino acid, has to be a triplet code. Has to do with the number of amino acids (20) and number of nucleic acid bases (4) 3 bases = 64 possible codons, which is enough. Using genetic code: on one end of the trna, there is an anticodon which is written 3" to 5, mrna codons instruct the ribosome to incorporate specific amino acids into a polypeptide - Translation: each codon codes for a specific amino acid. Decoding the genetic code: done by marshall w. nirenberg and philip leder, technique uses ribosome-bound transfer rnas (trnas) to decipher the code, many short mrnas with known codons are synthesized.
