BIOC 3300 Lecture Notes - Lecture 12: Pancreatic Lipase Family, Glycerol Kinase, Colipase

• School: Dalhousie University
• Department: Biochem & Molecular Biology
• Course: BIOC 3300
• Professor: Mc Leod Roger

Document Summary

Study online at quizlet. com/_17myyp: from phosphatidic acid, what enzymes catalyze the creation of. Tag: *phosphatidic acid phosphatase (pap) removes phosphate group to create diacylglycerol (dag), then diacylglycerol acyltransferase (dgat)* uses fatty acyl-coa to add a fatty acid to sn-3 position. *g3p acyltransferase (gpat), which adds once fatty acyl chain at a time using atp (energy from hydrolysis of ppi drives reaction*). After both chains have been added, phosphatidic acid is formed. In de novo biosynthesis of tag, what two enzymes catalyze the synthesis of g3p from. Where is glycerol transported so that it can be resynthesized back into. Lipase and procolipase form complex in presence of fa and bile salt micelles. Procolipase n- and c- terminal domains are cleaved to expose lipid-binding domains. Pancreatic lipase then conformationally changes to expose lipid-binding domain. Complex binds to micelle, catalytic triad reoriented to be exposed to. Tag + apolipoprotein chylomicrons: what determines the hormonal regulation activity of adipose tissue, what is a characteristic.