BIOC 3300 Lecture Notes - Lecture 9: Essential Fatty Acid, Carbon 15, Catabolism
4 Apr 2016
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Fatty acids with n-3 and n-6 double bonds. Animals cannot synthesize double bonds past c10 in the chain: what is the primary. Palmitate c16:0 product of fatty acid synthesis: why does fatty acid elongation occur in incriments of 2 carbon units? acetyl-coa introduces 2 carbons, what are the products of. 5 desaturase fatty acyl coa desaturase system, located on er cytoplasmic surface. Mostly in er but also in mitochondria: what is the substrate used in fatty acid elongation, and how is it different from fas"s substrate? fatty acid elongation uses. *thioesters: what are the steps involved in fatty acid elongation, what is the difference between mitochondrial and. Step 1 - condensation of long chain acyl-coa with malonyl-coa (catalyzed by one of two condensing enzymes, specific for saturated/unsaturated acyl substrates), forming a * -ketoacyl- Step 2 - -ketoacyl-coa is reduced, dehydrated, and reduced again by 2 nadph to give a saturated fatty acid that is 2 c"s longer.
