BIOC 2300 Lecture 4: BIOC 2300 - Lecture 4
18 Jan 2019
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Bioc 2300 lecture 4 january 14, 2019 nucleic acids, genomics, and dna technology: 1953: discovery of the dna double helix by watson and crick, 2018: first genetically engineered humans born (unconfirmed) Npc disease is a rapid genetic neurodegenerative disease whose symptoms start around school age. Nova scotia has the highest incidence rate in the world. It is traced back to ancestors of acadian decent. This disease was found to be a disease in membrane and cholesterol trafficking. A glycine into tryptophan mutation was the cause of this disease. The specificity of this disease (gene specificity) suggests that gene therapy could be a good treatment in the future. List the sources of human genome variability, and the types of mutations that impact protein structure: discuss several technologies used for genomic manipulation and analysis. Nucleotides are composed of nucleosides (composed of a nitrogenous base and a sugar). Nucleotide include the phosphate group as well as the sugar and nitrogenous bases.
