PSYC 441 Lecture Notes - Lecture 10: Frontal Lobe, Hyperactivation, Episodic Memory
28 Oct 2017
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Lecture 10 functional brain changes in sz: executive function, people with sz, have (frontal lobe) problems with: Selective attention: show activity in relevant regions important for working memory: Parietal cortex: why do we see increases and decreases in brain regions, graph, axis: As activity becomes hard, frontal cortex activation declines: another explanation: Patient and controls start at different locations (i. e. their curves are shifted): Sz patients would need to exert more pfc activity on the same task. Controls show greater activation than sz at the same level of diffi(cid:272)ulty (cid:894)i. e. ) patie(cid:374)ts (cid:272)a(cid:374)"t e(cid:374)gage their resour(cid:272)es(cid:895): wm and dlpfc function, study (callicott, 2003), experiment 1: 14 controls and 14 sz patients given a baseline task (i. e. the n-task): Just repeat what you see (i. e. no wm used). This is a baseline measure (important because to compare with other conditions). High-performance controls > high-performance sz > low- performance controls > low-performance sz. On the 2-back task (circles on the right):
