EXCI 210 Lecture Notes - Lecture 12: Bone Resorption, Hip Fracture, Dual-Energy X-Ray Absorptiometry

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Porosis = porous (cavities in the bone: dual-energy x-ray absorptiometry (dexa) Scans the entire body and measures the risk for fracture in the hip, spine, and wrist. The level of radiation is low and the test takes less than 5 minutes: quantitative compured tomography (qct) Measures bmd in the hip and spine and produces a three dimensional image that shows true volume density qct. The radiation level is 10 times higher than dexa: bmd measurement is given as a t-score and a z-score. T-score: the deviation from the mean bone density of healthy young adults of the same gender ethnicity. Z-score: the deviation from the mean bone density of adults of the same age and gender: the world health organization uses a t score of -2. 5 s. d ( and below) to define osteoporosis. Ex: drug use (corticosteroids, anticonvulsants, antirejection drugs etc. 1 out of 4 women over the age of 50 is affected.

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