ENGR 202 Lecture Notes - Lecture 11: Risk Assessment, Decision Analysis, Sampling Error
21 Jun 2015
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Document Summary
Risk = probability of a specific undesired: 2 primary categories of health risk: carcinogens and. = probability of undesired consequences x size of loss non-carcinogens. 4 steps for risk assessment: hazard assessment. Determine potential problem such as illness or health condition from exposure to a given chemical. Lab studies, animal studies, and epidemiological studies: dose response assessment. Mice rats: tumour development among samples, dose-response function, dose (mg/kg-da, average daily dose to represent long term (chronological) exposure, assumtion: Risk of cancel is never zero unless lifetime exposure is zero. Assume linear dose response relationship & same incident rate in both mice and people. Cancer development rate would be 10-5 x 2/100. = 2 in 10 million: carcenogenic chemicals. Cdi chronic daily intake: cdi mg/ kg-day = average daily dose mg. day / body weight kg, assume 70 years 70 kg body weight. Incremental life time cancer risk = cdi x pf. Level of acceptance risk: epa s lifetime risk level.
