BIOL 467 Lecture Notes - Lecture 21: Anoikis, Angiogenesis, Metastasis
Document Summary
Metastasis spread of cancer to other parts of the body. One a tumor has undergone metastasis some of the tumors can be small, beyond the detection of a surgeon. Maintain characteristics from the original tumor but may be still undergone changes that make them not respond to original therapies that you would have used for the primary tumour. Ma(cid:455) (cid:271)e at sites (cid:449)he(cid:396)e (cid:455)ou (cid:272)a(cid:374)(cid:859)t ad(cid:373)i(cid:374)iste(cid:396) the sa(cid:373)e t(cid:455)pe of the(cid:396)ap(cid:455), e(cid:454). Also talked to you about cancer as a lump of cells. Many cancer biologists view cancer is as a cancer and its niche. The niche becomes a fairly strong supporter or promoter of the cancer. So another approach is to worry about the niche/target the niche. Angiogenesis as a tumor progresses it reaches a point where it becomes nutrient deprived and. Steps of malignant tumor progression hypoxic unless it stimulates vessel growth.
