BIOL 366 Lecture Notes - Lecture 7: Paracrine Signalling, Tracheal Tube, Wnt Signaling Pathway

• School: Concordia University
• Department: Biology
• Course: BIOL 366
• Professor: Chiara Gamberi

Document Summary

Chimeric salamander and frog embryos following transplantation of embryonic tissue. Depe(cid:374)ds o(cid:374) the epitheliu(cid:373), (cid:449)hi(cid:272)h k(cid:374)o(cid:449)s ho(cid:449) to read the (cid:862)(cid:373)ake (cid:373)outh stru(cid:272)ture(cid:863) Transplanted flank ectoderm from an early frog gastrula to the region of a newt gastrula destined to become parts of the mouth (and vise versa) Salamander larvae with frog-like mouth and vis versa. The mesenchymal cells instructed the ectoderm to make a mouth, but the ectoderm responded by making the only kind of mouth it knew how to make, no matter how inappropriate. The instructions sent by the mesenchymal tissue can cross species barriers. Branchless signaling, breathless receptor induce the lead cell. Lead cell trails other epithelial cells connected via cadherin. 1 morphogen a diffusible biochemical molecule that can determine the fate of a cell by its concentration. When the (cid:373)orphoge(cid:374)"s (cid:272)o(cid:374)(cid:272)e(cid:374)tratio(cid:374) drops (cid:271)elo(cid:449) a (cid:272)ertai(cid:374) threshold, a different cell fate is specified. Beads releasing activing at different concentrations induce different gene sets.