NEUR 3403 Lecture Notes - Lecture 8: Growth Factor, Macrophage, Interferon Type I
20 Dec 2017
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Document Summary
Some of these bacteria can influence the functioning. Microbiota can influence the brain in many ways: lots of serotonin (70% comes from the gut, doesn"t enter the brain, affects other organs in other ways, affects the vagus nerve. Adaptive and acquired immunity: adaptive-> its learnt about something (ie chicken pox, acquired: Cytokine (interferon alpha: used to fight illnesses (ie skin cancer) Ido- > causes chemical changes -> kynurenine (cause destruction of serotonin neurons: tryptophon -> 5ht levels decline. Acutely stress and organism -> immune activation. Ido (shifts serotonin in another pathway and: not exclusive to depression, this pathway is a genral vulnerability pathway. Cholesterol building gup on the walls, more pressure builds up: more pressure -> more likely the cause damage, enough pressure can move plaque down. When dysbiosis occur -> peripheral inflammation (causes havoc with organ because its bad ) Crh 1 and crh2: chr1 emotional and cognitive symptoms, chr2 physical.
