NEUR 3401 Lecture Notes - Lecture 12: Sirolimus, Striatum, Cytoskeleton
21 Feb 2020
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Analysis measures total monitored 3 times for 24th locomotor activity. Pole test measure of motor control tested once coordination. Coordination catwalk sensors on catwalk to see paw placement chronic aadministration s. orgery of ctep rw. Rapamycin inhibits this path you can see in behavioural response ivproteinsynthesis prevents benefit al effects of ctep. Pd circuitry synuclein mutations d thalamus cerebellum it looks like the bg cortex are all important to pd. E e a e tremor u 25 dimmer switch hyp g bg is the switch that starts. 3 n pathology but the other parts controls how much pathology dimlintensity you cortet have also in bg we think that mostly in pons tremor motor cortex deep brain. Stn mostly for there are tremor neurons found. Cerebellum but not as much that connection is bidirectional. 0 stimulation is most effective tremours know these. A53t a 30p e46k familial pd cause x synuclein to fold in weird ways eventually lewy bodies linked to.
