NEUR 3204 Lecture Notes - Lecture 9: Choline Acetyltransferase, Botulinum Toxin, Choline

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Choline is bought in though diet choline acetyltransferase makes ach packaged. A bindingto autoreceptors most often to control rate of release. 7 choline gets re used aceticacid water soluble washes out. Acetate breaks it down to choline acetic acid there is some in psn but mostly in membrane of pstsn. Ache acetylcholinesterase nachr musclecontractions nmt ionotropic agonistc activatesmolecules whenactivated it allows nat catz in each diff brain region has diff brain subtypes of the receptor each subtype may have diff have atleast. 482 on pre synaptic neuron allows ca12 influx when nicotine binds a reuse of neurotrans of binding sites at jxn of l subunit. 1 a subunit for it to f1 i it must. Machr parasymp nervous system metabotropic stimulation of k channelopening which leads to hyperpol firing depending on wherethe receptor is found it will do differentthings. M2 m4 gygo mh adenylatecyclase parasympathetic i reduction in cell closes cat 2 channels t contraction strength.

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