NEUR 3200 Lecture Notes - Lecture 3: Tufted Cell, Olfactory Bulb, Olfactory System
17 Dec 2017
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* in the textbook orn and osn are interchangeable. If there"s no need, mutations occur to make some receptors non functional. Binding causes conformational changes to the protein. Can act on ion channels or cause intracellular signals. Cations will be let in, causing depolarization. Increased calcium ows into the cell, causing chloride channels to open, letting chloride out of the cell. The membrane potential becomes more positive, causing further depolarization. Only odourants can bind to the receptor proteins. * good to know for short answer questions. * also be able to compare to other processes. Action potentials occur if graded potentials reach the olfactory receptor cell. Multiple mitral cells branch from the glomerulus. Each avour of olfactory receptor goes to a part in the olfactory bulb (allows for high sensitivity) Tufted cells are a subdivision of mitral cells. Spatial maps in olfactory bulb - show which glomeruli are activated for different odorants.
