NEUR 2200 Lecture Notes - Lecture 8: Acetylcholinesterase, Bradycardia, Cholinergic
28 Feb 2017
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Two types of synapsis: chemical: the junction where neurotransmitters are realised from one presynaptic cleft to the postsynaptic cleft. Synaptic cleft: small gap in-between the postsynaptic and presynaptic membrane. Axodendritic: axon terminals send messages directly to dendrites (most common) Axoextracellular: axon terminal send messages to no specific target (extracellular fluid) Axosomatic: axon terminal sends messages directly to cell body (normally inhibitory responses by interneurons) Axosynaptic: axon terminal sends messages directly to another terminal. Axoaxonic: axon terminal sends messages directly too another axon. Axosecretory: ends on a blood vessel and sends neurotransmitters into the blood: electrical. Gap junction: fused presynaptic and postsynaptic membrane that allow action potentials to pass using electrical synapses (these are old ways of communication such as bacteria). Synthesised from one part nutrients transported from blood, and the other from synthesised mrna, and used in axon terminals. Examples: acetylcholine, amines: dopamine, norepinephrine, epinephrine, serotonin, amino acids: glutamate, gamma-aminobutyric, glycine.
