BIOL 2303 Lecture Notes - Lecture 18: Drug Resistance, Parallel Evolution, Dna Gyrase
2 Nov 2020
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It is difficult to study these question experimentally: this is the case because evolution is a process that takes a long time to observe. Make inferences about history from extant variation: between species or within population. Fossil record: there are fossils from a variety of phyla that can be found in the burgess shale which can tell us about evolution of species (morphology) Fossils, the burgess shale, and the tape of life. Gould thought that the burgess shale provided evidence that evolution is highly contingent: the divine tape recorder holds millions of scenarios, each perfectly sensible. Use of experimental evolution motivated by the long time take for most real world evolution . Learn about the principles of evolution from laboratory experiments. Richard lenski has the longest running laboratory selection experiment. In 1988, started 12 replicate populations of e. coli: long term evolution experiment (ltee) This is a gram-negative opportunistic pathogen (colonizes wet environments)
