BIOL 1010 Lecture Notes - Lecture 3: Single-Nucleotide Polymorphism, Arthur Kornberg, Mendelian Inheritance
Document Summary
#denaturation is also called melting of dna and annealing is also called hybridization . Dna strands with similar sequences will form partial duplexes or hybrids with each other. This property is used to sh out a similar gene from di erent species, if the gene sequence from a species is known as closer evolutionary relationship between species means more similar dna sequences. A process which vividly paints chromosomes or portions of chromosomes with uorescent. It identi es chromosomal abnormalities, aids in gene mapping, toxicological studies, analysis of chromosome, structural aberrations, and ploidy determination. Independent assortment produces 2^n distinct gametes, where n = the number of unique chromosomes. In humans, n = 23 and 2^23 8,000,0000. #in dna guanine and cytosine are bound by 3 hydrogen bonds while adenine and thymine are bound by 2 hydrogen bonds. Single nucleotide polymorphism (snp): (or single nucleotide variant-snv) A variation in a single nucleotide that occurs at a speci c position in the genome.