SCIE 1P51 Lecture Notes - Lecture 4: Pertussis, Model Organism, Cohort Study
16 Sep 2016
School
Department
Course
Professor
Document Summary
Continuation from monday lecture 3: 2007: cdc and vaccine data safety network published retrospective cohort study on neuropsychological outcomes in 1047 children aged 7-10 years old and found no deleterious effects from early thimerosal exposure (thompson et al. ) Thimerosal vaccine data safety network: make reports, when there is a world wide disease, allow data to be shared with other researchers, large case-control study of autism and thimerosal exposure currently in data collecting phase. People are worried about this with their children as there is now a spectrum linking their children developing this; noticed changes once getting this vaccine so they assume. Want find a direct link but so far have been unsuccessful. Testing vaccines safety: synthesize it in the lab. Human testing: phase 1 iv (everything looked fine) If the intervention did not have any nasty safety profile, move on to next phase: phase 2 (dealing with healthy individuals)
